Biological slime is in the role of heterotrophic bacteria in the water of colloidal suspensions as the main material bonded together viscous substance. Due to the presence of biological slime and impede normal cooling water through, reducing the cooling effect of the condenser. Biological slime covering the water side of the heat exchanger metal surfaces to prevent corrosion and scale inhibitor to reach the metal surface to play a role in normal corrosion and scale, reducing the effectiveness of these drugs. Slime covering the metal surface to form a heterotrophic potential to accelerate the corrosion rate of the metal. A large amount of slime in particular algae, attached to the device surface of the cooling water system is not only affects the appearance of the system, but also may cause clogging of heat exchange equipment and anaerobic corrosion. By penetrant, surfactant, release agent consisting of sludge remover liquid from A and B were composed according to the specific use to run the program live on the implementation of the development.